Do you have the latest travel health recommendations? Use the new CDC Health Information for International Travel (the Yellow Book) for. The Yellow Book includes important travel medicine updates: • The latest information about emerging infectious disease threats such as. CDC Health Information for International Travel (commonly called the Yellow Book) is published every two years as a reference for health professionals.

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and Clinicians. CDC Travelers' Health Branch. Page 2. Yellow Fever Yellow Book Also available online: CDC Yellow Book Health Information for International Travel (Cdc Health Information for International Travel): Medicine & Health. As the number of international travelers and their range of itineraries increases, protecting the health of those travelers and of the communities.

Want the latest travel health recommendations?

What is the Yellow Book? It is written primarily for health care providers, including doctors, nurses, and pharmacists, who help travelers prepare for upcoming trips.

The book offers an in-depth look at travel health risks and ways to prevent them, advice for people with special travel health needs, and more. People in the travel industry, international corporations, missionary and volunteer organizations, people who live abroad, and even travelers on short trips also find the Yellow Book an excellent resource.

What information can I find in the Yellow Book? Topics in the Yellow Book include: Updated vaccine requirements and recommendations.

New 2018 Yellow Book Available

Diseases related to travel: what causes them, where they occur, how to prevent them, and how to diagnose and treat them. New Yellow Book Available. Recommend on Facebook Tweet Share Compartir. What is the Yellow Book?

A world of health all in one book! Features Media Sign up for Features. File Formats Help: Only one yellow fever vaccine is licensed for use in the United States Table Studies comparing the reactogenicity and immunogenicity of various yellow fever vaccines, including those manufactured outside the United States, suggest that there is no substantial difference in the reactogenicity or immune response generated by the various vaccines.

New 2018 Yellow Book Available

Thus, people who receive yellow fever vaccines in other countries should be considered protected against yellow fever. In addition, some countries require proof of yellow fever vaccination for entry.

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Because of the risk of serious adverse events after yellow fever vaccination, clinicians should only vaccinate people who 1 are at risk of exposure to YFV or 2 require proof of vaccination to enter a country. To further minimize the risk of serious adverse events, clinicians should carefully observe the contraindications and consider the precautions to vaccination before administering yellow fever vaccine Table However, in , the WHO Strategic Advisory Group of Experts on Immunization concluded that a single primary dose of yellow fever vaccine provides sustained immunity and lifelong protection against yellow fever disease and that a booster dose is not needed.

That year the World Health Organization adopted the recommendation to remove the year booster dose requirement from the IHR after a 2-year transition period. As of July 11, , a completed International Certificate of Vaccination or Prophylaxis is valid for the lifetime of the vaccinee and countries cannot require proof of revaccination booster against yellow fever as a condition of entry, even if the last vaccination was more than 10 years prior.

The Advisory Committee on Immunization Practices ACIP also stated that a single dose of yellow fever vaccine provides long-lasting protection and is adequate for most travelers. However, these guidelines specify that additional doses of yellow fever vaccine are recommended for the following groups of travelers: Women who were pregnant when they received their initial dose of vaccine: they should receive 1 additional dose of yellow fever vaccine before their next travel that puts them at risk for yellow fever.

People who received a hematopoietic stem cell transplant after receiving a dose of yellow fever vaccine: they should be revaccinated before their next travel that puts them at risk for yellow fever as long as they are sufficiently immunocompetent to be safely vaccinated.

People who were infected with HIV when they received their last dose of yellow fever vaccine: they should receive a dose every 10 years if they continue to be at risk for yellow fever virus infection. This would include travelers who plan to spend a prolonged period in endemic areas, or those traveling to highly endemic areas such as rural West Africa during peak transmission season or an area with an ongoing outbreak.

Although booster doses of yellow fever vaccine are not recommended for most travelers, and despite the recent changes to the IHR, clinicians and travelers should review the entry requirements for destination countries. At the time this edition goes to press it is uncertain when and if all countries with yellow fever vaccination requirements will adopt and fully implement this change that is stipulated by the IHR.

Explore Travel Health with the CDC Yellow Book

Reported events typically include low-grade fever, headache, and myalgia that begin within days after vaccination and last 5—10 days. Anaphylaxis after yellow fever vaccine is reported to occur at a rate of 1. Historically, YEL-AND was seen primarily among infants as encephalitis, but more recent reports have been among people of all ages. The onset of illness for documented cases in the United States is 2—56 days after vaccination. This contraindication was instituted in the late s in response to a high rate of YEL-AND documented in vaccinated young infants 50— per , The mechanism of increased neurovirulence in infants is unknown but may be due to the immaturity of the blood-brain barrier, higher or more prolonged viremia, or immune system immaturity.

The stopper used in vials of vaccine also contains dry natural latex rubber, which may cause an allergic reaction.

Health Information for International Travel

If vaccination of a person with a questionable history of hypersensitivity to any of the vaccine components is considered essential because of a high risk for acquiring yellow fever, skin testing, as described in the vaccine package insert, should be performed under close medical supervision.

If a person has a positive skin test to the vaccine or has severe egg sensitivity and the vaccination is recommended, desensitization, as described in the package insert, can be performed under direct supervision of a physician experienced in the management of anaphylaxis.

If travel to a yellow fever—endemic area cannot be avoided in a person with such a thymus disorder, a medical waiver should be provided and counseling on protective measures against mosquito bites should be emphasized. Because there is no evidence of immune dysfunction or increased risk of yellow fever vaccine—associated serious adverse events in people who have undergone incidental surgical removal of their thymus or have had indirect radiation therapy in the distant past, these people can be given yellow fever vaccine if recommended or required.

This recommendation is based on a potential increased risk of encephalitis in this population. See the following section, Precautions, for other HIV-infected people not meeting the above criteria.Both authors: No reported conflicts.

Table of Contents

The information is a good overview that is as detailed as space allows. The text is supplemented by country-specific and disease-specific maps, and by easily interpretable tables and figures that summarize guidelines and recommendations. The edition is a book containing eight chapters that span about pages.

I highly recommend this book.